Temporal dynamics of gut microbiomes in non-industrialized urban Amazonia.

ABSTRACT: Increasing levels of industrialization have been associated with changes in gut microbiome structure and loss of features thought to be crucial for maintaining gut ecological balance. The stability of gut microbial communities over time within individuals seems to be largely affected by these changes but has been overlooked among transitioning populations from low- to middle-income countries. Here, we used metagenomic sequencing to characterize the temporal dynamics in gut microbiomes of 24 individuals living an urban non-industrialized lifestyle in the Brazilian Amazon. We further contextualized our data with 165 matching longitudinal samples from an urban industrialized and a rural non-industrialized population. We show that gut microbiome composition and diversity have greater variabili

SUBMITTER: Schaan AP 

PROVIDER: S-EPMC10997323 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature