Physics-Informed Discretization for Reproducible and Robust Radiomic Feature Extraction Using Quantitative MRI.

ABSTRACT:

Objective

Given the limited repeatability and reproducibility of radiomic features derived from weighted magnetic resonance imaging (MRI), there may be significant advantages to using radiomics in conjunction with quantitative MRI. This study introduces a novel physics-informed discretization (PID) method for reproducible radiomic feature extraction and evaluates its performance using quantitative MRI sequences including magnetic resonance fingerprinting (MRF) and apparent diffusion coefficient (ADC) mapping.

Materials and methods

A multiscanner, scan-rescan dataset comprising whole-brain 3D quantitative (MRF T1, MRF T2, and ADC) and weighted MRI (T1w MPRAGE, T2w SPACE, and T2w FLAIR) from 5 healthy subjects was prospectively acquired. Subjects underwent 2 repeated acquisiti

SUBMITTER: Zhao W 

PROVIDER: S-EPMC10997475 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature