Systematic review and meta-analysis of the management of acute uncomplicated diverticulitis: time to change traditional practice.

ABSTRACT:

Background

To evaluate comparative outcomes of outpatient (OP) versus inpatient (IP) treatment and antibiotics (ABX) versus no antibiotics (NABX) approach in the treatment of uncomplicated (Hinchey grade 1a) acute diverticulitis.

Methods

A systematic online search was conducted using electronic databases. Comparative studies of OP versus IP treatment and ABX versus NABX approach in the treatment of Hinchey grade 1a acute diverticulitis were included. Primary outcome was recurrence of diverticulitis. Emergency and elective surgical resections, development of complicated diverticulitis, mortality rate, and length of hospital stay were the other evaluated secondary outcome parameters.

Results

The literature search identified twelve studies (n = 3,875) comparing NABX (n =

SUBMITTER: Mohamedahmed AY 

PROVIDER: S-EPMC10997545 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature