Efficacy and safety of lenalidomide in the treatment of B-cell non-Hodgkin lymphoma.

ABSTRACT:

Background

The combination of rituximab and chemotherapy is a first-line treatment for patients with B-cell non-Hodgkin lymphoma. Lenalidomide is an immunomodulatory drug that has shown promising properties and activity in a variety of hematological malignancies. This study evaluated the efficacy and safety of lenalidomide-based regimens in the treatment of B-cell non-Hodgkin lymphoma.

Methods

The PubMed, Science Direct, ClinicalTrials.gov, and Web of Science databases were searched for relevant studies published up to May 2022. Studies with patients diagnosed with non-Hodgkin B-cell lymphoma, who were randomly assigned to a lenalidomide treatment group or a non-lenalidomide control group were considered for inclusion in this review and meta-analysis. Pooled hazard ratios (H

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10997569 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature