Calcium imaging of adult olfactory epithelium reveals amines as important odor class in fish.

ABSTRACT: The odor space of aquatic organisms is by necessity quite different from that of air-breathing animals. The recognized odor classes in teleost fish include amino acids, bile acids, reproductive hormones, nucleotides, and a limited number of polyamines. Conversely, a significant portion of the fish olfactory receptor repertoire is composed of trace amine-associated receptors, generally assumed to be responsible for detecting amines. Zebrafish possess over one hundred of these receptors, but the responses of olfactory sensory neurons to amines have not been known so far. Here we examined odor responses of zebrafish olfactory epithelial explants at the cellular level, employing calcium imaging. We report that amines elicit strong responses in olfactory sensory neurons, with a time course char

SUBMITTER: Dieris M 

PROVIDER: S-EPMC10997700 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature