Postmastectomy radiation therapy in breast cancer patients with micrometastatic disease in sentinel node dissection: A cohort study and meta-analysis.

ABSTRACT:

Aim

The potential role of postmastectomy radiation therapy (PMRT) on prognosis in patients with T1-2 breast cancer and micrometastatic disease in sentinel lymph node dissection (SLND) has not yet been established. The aim of this study was to investigate the impact of PMRT on prognosis in patients with T1-2 breast cancer and micrometastatic in SLND.

Method

A register- and population-based cohort was utilized by identifying eligible patients on the research database BcBase 3.0. Multivariate Cox regression models were applied for survival outcomes. In addition, a systematic literature review and meta-analysis including all relevant studies on this topic was performed.

Results

In total, 956 patients fulfilling the inclusion criteria were found through the BcBaSe 3

SUBMITTER: Jafer F 

PROVIDER: S-EPMC10998037 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature