Common Seasonal Pathogens and Epidemiology of Henoch-Schonlein Purpura Among Children.

ABSTRACT:

Importance

Henoch-Schönlein purpura (HSP) is the most common type of vasculitis in children. The factors that trigger the disease are poorly understood. Although several viruses and seasonal bacterial infections have been associated with HSP, differentiating the specific associations of these pathogens with the onset of HSP remains a challenge due to their overlapping seasonal patterns.

Objective

To analyze the role of seasonal pathogens in the epidemiology of HSP.

Design, setting, and participants

This cohort study comprised an interrupted time-series analysis of patient records from a comprehensive national hospital-based surveillance system. Children younger than 18 years hospitalized for HSP in France between January 1, 2015, and March 31, 2023, were included.

SUBMITTER: Felix A 

PROVIDER: S-EPMC10998156 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature