Perifocal edema is a risk factor for preoperative seizures in patients with meningioma WHO grade 2 and 3.

ABSTRACT:

Background

Patients with intracranial meningiomas frequently suffer from tumor-related seizures prior to resection, impacting patients' quality of life. We aimed to elaborate on incidence and predictors for seizures in a patient cohort with meningiomas WHO grade 2 and 3.

Methods

We retrospectively searched for patients with meningioma WHO grade 2 and 3 according to the 2021 WHO classification undergoing tumor resection. Clinical, histopathological and imaging findings were collected and correlated with preoperative seizure development. Tumor and edema volumes were quantified.

Results

Ninety-five patients with a mean age of 59.5 ± 16.0 years were included. Most tumors (86/95, 90.5%) were classified as atypical meningioma WHO grade 2. Nine of 95 tumors (9.5%) correspond

SUBMITTER: Teske N 

PROVIDER: S-EPMC10998776 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature