Age-related markers and predictors of diabetic kidney disease progression in type 2 diabetes patients: a retrospective cohort study.

ABSTRACT:

Background

Diabetic kidney disease (DKD) is characterized by reduced estimated glomerular filtration rate (eGFR) and albuminuria, which play a pivotal role in both diagnosing and determining the disease's progression. This study aimed to assess the trajectory of these markers concerning age in individuals with DKD and identify predictive factors for the decline in eGFR decline, variation in albuminuria, mortality, and progression to renal replacement therapy (RRT).

Design

This retrospective cohort encompassed patients with type 2 diabetes (T2D), divided into two age categories: <75 and ⩾75 years old.

Methods

Over a 3-year span, the study evaluated eGFR (CKD-EPI) and 24-h albuminuria. Univariate and multivariate analyses were employed to pinpoint factors associated wit

SUBMITTER: Fabre L 

PROVIDER: S-EPMC10999127 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature