Predicting perimetric defects from en face maps of retinal nerve fibre layer reflectance.

ABSTRACT:

Purpose

To develop criteria to predict visual hemifields with deep perimetric defects based on retinal nerve fibre layer (RNFL) reflectance, in a transparent process whose components can be assessed by independent laboratories analysing data from their own small groups.

Methods

The analysis was carried out in four stages, using three independent groups of patients-30, 33 and 62 participants-with glaucoma and age-similar controls. The first stage used Group 1 to develop a criterion for RNFL reflectance images at 24, 36 or 48 μm below the inner limiting membrane (ILM). The second stage evaluated the criterion using Group 2. The third stage developed a second criterion to improve performance for Groups 1 and 2 combined. The fourth stage evaluated the second criterion with Group

SUBMITTER: Swanson WH 

PROVIDER: S-EPMC10999345 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature