Stimulant use and opioid-related harm in patients on long-term opioids for chronic pain.

ABSTRACT:

Background

There is lack of clarity regarding the impact of and optimal clinical response to stimulant use among people prescribed long-term opioid therapy (LTOT) for pain.

Objective

To determine if a positive urine drug test (UDT) for stimulants was associated with subsequent opioid-related harm or discontinuation of LTOT.

Design

Retrospective cohort study.

Patients

People living with and without HIV living in a major metropolitan area with public insurance, prescribed LTOT for chronic, non-cancer pain (n=600).

Main measures

UDT results from January 2012 to June 2019 were evaluated against 1) opioid-related emergency department (ED) visits (oversedation, constipation, infections associated with injecting opioids, and opioid seeking) or death in each 90-

SUBMITTER: Appa A 

PROVIDER: S-EPMC10999379 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature