Diagnostic yield of FAP-guided positron emission tomography in thyroid cancer: a systematic review.

ABSTRACT:

Background

Several recent studies have proposed the possible application of positron emission tomography/computed tomography (PET/CT) administering radiolabelled fibroblast-activation protein (FAP) inhibitors for various forms of thyroid cancer (TC), including differentiated TC (DTC), and medullary TC (MTC).

Methods

The authors conducted an extensive literature search of original studies examining the effectiveness of FAP-guided PET/CT in patients with TC. The papers included were original publications exploring the use of FAP-targeted molecular imaging in restaging metastatic DTC and MTC patients.

Results

A total of 6 studies concerning the diagnostic yield of FAP-targeted PET/CT in TC (274 patients, of which 247 DTC and 27 MTC) were included in this systematic revie

SUBMITTER: Rizzo A 

PROVIDER: S-EPMC10999586 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature