Elevated troponin levels as a predictor of mortality in patients with acute stroke: a systematic review and meta-analysis.

ABSTRACT:

Background and aim

The prognostic potential of cardiac troponin (cTn) in acute stroke patients has been a subject of ongoing debate. Our objective was to provide a comprehensive evidence for predicting mortality in acute stroke patients by using the elevated troponin levels.

Methods

We conducted an extensive literature search, including PubMed, EMbase, and Trip Databases, covering studies published up to September 30, 2023. We computed risk ratios (RR) with 95% confidence intervals (CIs), performed sensitivity analysis, and conducted trial sequential analysis (TSA).

Results

In total, 53 studies were analyzed, with 37 focusing on acute ischemic stroke (AIS), 11 on subarachnoid hemorrhage (SAH), and 7 on Intracerebral hemorrhage (ICH). Elevated cTn levels were significa

SUBMITTER: Gulia A 

PROVIDER: S-EPMC10999611 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature