Linguistic changes in neurodegenerative diseases relate to clinical symptoms.

ABSTRACT:

Background

The detection and characterization of speech changes may help in the identification and monitoring of neurodegenerative diseases. However, there is limited research validating the relationship between speech changes and clinical symptoms across a wide range of neurodegenerative diseases.

Method

We analyzed speech recordings from 109 patients who were diagnosed with various neurodegenerative diseases, including Alzheimer's disease, Frontotemporal Dementia, and Vascular Cognitive Impairment, in a cognitive neurology memory clinic. Speech recordings of an open-ended picture description task were processed using the Winterlight speech analysis platform which generates >500 speech features, including the acoustics of speech and linguistic properties of spoken language.

SUBMITTER: Gumus M 

PROVIDER: S-EPMC10999640 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature