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Proposal of statistical twin as a transition to full digital twin technology for cardiovascular interventions.


ABSTRACT:

Objectives

We introduced statistical twin as aggregates of multiple virtual patients' data throughout the treatment at any chosen time point. The goal of this manuscript was to provide the proof of concept of statistical twin by evaluating the feasibility of detection of distinctive aggregates of patients throughout the perioperative trajectory (prerequisite for development of statistical twin).

Methods

We used a retrospective validated cohort of all comers with mitral valve disease treated (2014-2020) at a tertiary academic hospital. The end point was overall survival based on the decision of the heart team. We applied two-step cluster analysis to detect distinct aggregated virtual patients throughout the process of care.

Results

The cluster procedure resulted in 5 d

SUBMITTER: Sardari Nia P 

PROVIDER: S-EPMC11001486 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature