L-cysteine contributes to destructive activities of odontogenic cysts/tumor.

ABSTRACT:

Background

Odontogenic cysts/tumor can cause severe bone destruction, which affects maxillofacial function and aesthetics. Meanwhile, metabolic reprogramming is an important hallmark of diseases. Changes in metabolic flow affect all aspects of disease, especially bone-related diseases. At present, the researches on pathogenesis of odontogenic cysts/tumor are mainly focused on the level of gene regulation, but the effects of metabolic alterations on odontogenic cysts/tumor have still underexplored.

Materials and methods

Imaging analysis was used to evaluate the lesion size of different odontogenic lesions. Tartrate resistant acid phosphatase (TRAP) and immunohistochemistry (IHC) assays were utilized to detect the differences in bone destruction activity in odontogenic cysts a

SUBMITTER: Li J 

PROVIDER: S-EPMC11001836 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature