Assessment of fetal corpus callosum biometry by 3D super-resolution reconstructed T2-weighted magnetic resonance imaging.

ABSTRACT:

Objective

To assess the accuracy of corpus callosum (CC) biometry, including sub-segments, using 3D super-resolution fetal brain MRI (SR) compared to 2D or 3D ultrasound (US) and clinical low-resolution T2-weighted MRI (T2WS).

Method

Fetal brain biometry was conducted by two observers on 57 subjects [21-35 weeks of gestational age (GA)], including 11 cases of partial CC agenesis. Measures were performed by a junior observer (obs1) on US, T2WS and SR and by a senior neuroradiologist (obs2) on T2WS and SR. CC biometric regression with GA was established. Statistical analysis assessed agreement within and between modalities and observers.

Results

This study shows robust SR to US concordance across gestation, surpassing T2WS. In obs1, SR aligns with US, except for genu an

SUBMITTER: Lamon S 

PROVIDER: S-EPMC11002102 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature