Intravesical Interferon Therapy vs Hyaluronic Acid for Pain Among Female Individuals With Interstitial Cystitis: A Randomized Clinical Trial.

ABSTRACT:

Importance

Interstitial cystitis (IC) is a debilitating condition. Although viral infection is a potential etiological cause, few studies have detected the effect of antiviral treatment.

Objective

To determine the efficacy and safety of intravesical interferon instillation compared with hyaluronic acid in female patients with IC.

Design, setting, and participants

This double-masked, randomized phase 2/3 clinical trial with parallel group design was implemented from October 2022 to April 2023 and had a 6-month follow-up period. The study was conducted at a single center. Eligible participants were female patients aged 18 to 70 years with a diagnosis of IC for more than 6 months. The last visit took place in October 2023. Data were analyzed between October and November

SUBMITTER: Shen SH 

PROVIDER: S-EPMC11002698 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature