Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study.

ABSTRACT:

Background

Sepsis-induced myocardial injury is a serious complication of sepsis. QT prolongation is a proarrhythmic state which reflects myocardial injury in a group of heterogeneous disorders. However, the study on the clinical value of QT prolongation in sepsis is limited.

Methods

We aimed to investigate the clinical characteristics and predictors of new-onset QT prolongation in sepsis and its impact on the outcome in a multicenter retrospective cohort study. Electrocardiographic and clinical data were collected from patients with sepsis from the wards and intensive care units of four centers after exclusion of QT-influencing medications and electrolyte abnormalities. Clinical outcomes were compared between patients with and without QT prolongation (QTc > 450 ms). Multivar

SUBMITTER: Liu W 

PROVIDER: S-EPMC11003155 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature