Ipsilateral and contralateral coadministration of influenza and COVID-19 vaccines produce similar antibody responses.

ABSTRACT:

Background

World Health Organisation (WHO) and USA Centers for Disease Control and Prevention (U.S. CDC) recommendations now allow simultaneous administration of COVID-19 and other vaccines. We compared antibody responses after coadministration of influenza and bivalent COVID-19 vaccines in the same (ipsilateral) arm vs. different (contralateral) arms.

Methods

Pre- and post-vaccination serum samples from individuals in the Prospective Assessment of COVID-19 in a Community (PACC) cohort were used to conduct haemaglutination inhibition (HI) assays with the viruses in the 2022-2023 seasonal influenza vaccine and focus reduction neutralisation tests (FRNT) using a BA.5 SARS-CoV-2 virus. The effect of ipsilateral vs. contralateral vaccination on immune responses was inferred in a

SUBMITTER: Pattinson D 

PROVIDER: S-EPMC11004685 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature