Chemical constituents of the roots of Kniphofia schimperi and evaluation of their antimicrobial activity.

ABSTRACT: Kniphofia schimperi is one of the endemic plants of Ethiopia and is widely used for the treatment of microbial infections. However, the biological and phytochemical information pertaining to this plant has not been reported so far. Anticipated by these claims, the chromatographic isolation of the CHCl₃/CH₃OH (1:1 v/v) extract of the roots of K. schimperi afforded five compounds, viz., knipholone (1), asphodeline (2), β-sitosterol (3), 9-pentacosenoic acid (4), and nonacosanoic acid (5). The structures of the isolated compounds were identified based on their NMR (1D and 2D) spectral data analysis and comparison with reported literature data. The crude extract and isolated compounds were evaluated for

SUBMITTER: Deresa EM 

PROVIDER: S-EPMC11004798 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature