Accumulation of Ambient Black Carbon Particles Within Key Memory-Related Brain Regions.

ABSTRACT:

Importance

Ambient air pollution is a worldwide problem, not only related to respiratory and cardiovascular diseases but also to neurodegenerative disorders. Different pathways on how air pollutants could affect the brain are already known, but direct evidence of the presence of ambient particles (or nanoparticles) in the human adult brain is limited.

Objective

To examine whether ambient black carbon particles can translocate to the brain and observe their biodistribution within the different brain regions.

Design, setting, and participants

In this case series a label-free and biocompatible detection technique of nonincandescence-related white light generation was used to screen different regions of biobanked brains of 4 individuals from Belgium with neuropathological

SUBMITTER: Vanbrabant K 

PROVIDER: S-EPMC11004827 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature