Risk-factor analysis for extended-spectrum beta-lactamase-producing Enterobacterales colonization or infection: Evaluation of a novel approach to assess local prevalence as a risk factor.

ABSTRACT:

Objective

To explore an approach to identify the risk of local prevalence of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) on ESBL-E colonization or infection and to reassess known risk factors.

Design

Case-control study.

Setting

Johns Hopkins Health System emergency departments (EDs) in the Baltimore-Washington, DC, region.

Patients

Patients aged ≥18 years with a culture growing Enterobacterales between April 2019 and December 2021. Cases had a culture growing an ESBL-E.

Methods

Addresses were linked to Census Block Groups and placed into communities using a clustering algorithm. Prevalence in each community was estimated using the proportion of ESBL-E among Enterobacterales isolates. Logistic regression was used to determine risk fa

SUBMITTER: Cherian JP 

PROVIDER: S-EPMC11005063 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature