Resistance training's impact on blood biomarkers and cognitive function in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial.

ABSTRACT:

Background

The aging brain exhibits a neuroinflammatory state, driven partly by peripheral pro-inflammatory stimuli, that accelerates cognitive deterioration. A growing body of evidence clearly indicates that physical exercise partly alleviates neuroinflammation and positively affects the aging process and cognition. In this randomized controlled trial, we aimed to observe the effect of 12 weeks of resistance training (RT) on peripheral biomarker levels, cognitive function changes and their interrelationship, and explore differences in those exercise-induced changes in older adults with high risk of mild cognitive impairment (MCI) compared to older adults with low risk of MCI.

Methods

Fifty-two participants (aged 60-85 years old, 28 female) were randomly allocated to a 12 w

SUBMITTER: Vints WAJ 

PROVIDER: S-EPMC11005144 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature