Cytokine profile in peripheral blood mononuclear cells differs between embryo donor and potential recipient sows.

ABSTRACT:

Introduction

Pregnancy success relies on the establishment of a delicate immune balance that requires the early activation of a series of local and systemic immune mechanisms. The changes in the immunological profile that are normally occurring in the pregnant uterus does not take place in cyclic (non-pregnant) uterus, a fact that has been widely explored in pigs at the tissue local level. Such differences would be especially important in the context of embryo transfer (ET), where a growing body of literature indicates that immunological differences at the uterine level between donors and recipients may significantly impact embryonic mortality. However, whether components of peripheral immunity also play a role in this context remains unknown. Accordingly, our hypothesis is that th

SUBMITTER: Cambra JM 

PROVIDER: S-EPMC11006195 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature