Is there a link between appendicitis and the risk of diverticular disease?: a large German cohort study.

ABSTRACT:

Purpose

Appendicitis, characterized by inflammation of the vermiform appendix, is a common abdominal emergency necessitating appendectomy. Recent evidence suggests a potential link between appendicitis and subsequent diverticular disease, yet population-based studies investigating this association are limited.

Methods

Utilizing the Disease Analyzer database encompassing data from over 1000 primary care practices in Germany, we conducted a retrospective cohort study. We included 25,379 adults diagnosed with appendicitis and an equal number of matched controls without appendicitis. The incidence of diverticular disease over a 10-year follow-up period was compared between the two cohorts. Cox regression analysis was performed to assess the association between appendicitis and d

SUBMITTER: Krieg S 

PROVIDER: S-EPMC11006757 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature