Physical activity decreases in patients on the liver transplant waiting list and influences postoperative outcome-a prospective cohort study.

ABSTRACT:

Background

Physical deconditioning affects patients suffering from end-stage liver disease (ESLD). Liver transplantation (LT) is the only curative option for ESLD. Growing evidence suggests that pre-habilitation is beneficial in reducing post-surgical morbidity and mortality. We investigated physical activity (PA) in patients awaiting LT in a country with long waiting times.

Methods

Prospective, single center, longitudinal study in Bern, Switzerland between June 2019 and February 2020 (halted due to SARS-CoV-2 pandemic), with follow-up data up to six months post-transplant. Patients were instructed to use a wrist tracker (FitBit) to monitor PA, which was assessed using mixed-effects generalized linear models. The study was approved by the local ethics committee (BASEC ID 201

SUBMITTER: Magyar CTJ 

PROVIDER: S-EPMC11007345 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature