Compared with SonoVue^® LR-5, Sonazoid^® modified LR-5 has better diagnostic sensitivity for hepatocellular carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

The contrast-enhanced ultrasound (CEUS) liver imaging reporting and data system (LI-RADS) is a standardized system for reporting liver nodules in patients at risk of developing hepatocellular carcinoma (HCC) and is only recommended for pure blood pool agents such as SonoVue^®. A modified LI-RADS was proposed for Sonazoid^®, a Kupffer cell-specific contrast agent. This meta-analysis was conducted to compare the diagnostic efficiency of the CEUS LI-RADS for SonoVue^® and the modified LI-RADS for Sonazoid^®.

Methods

The PubMed, Medline, Web of Science, Embase, and Cochrane Library databases were systematically searched to retrieve studies on the diagnostic efficiency of the CEUS LI-RADS algorithms in diagnosing HCC using SonoVu

SUBMITTER: Cao J 

PROVIDER: S-EPMC11007517 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature