Minimally invasive surgery for clinical T4 non-small-cell lung cancer: national trends and outcomes.

ABSTRACT:

Objectives

Recent randomized data support the perioperative benefits of minimally invasive surgery (MIS) for non-small-cell lung cancer (NSCLC). Its utility for cT4 tumours remains understudied. We, therefore, sought to analyse national trends and outcomes of minimally invasive resections for cT4 cancers.

Methods

Using the 2010-2019 National Cancer Database, we identified patients with cT4N0-1 NSCLC. Patients were stratified by surgical approach. Multivariable logistic analysis was used to identify factors associated with use of a minimally invasive approach. Groups were matched using propensity score analysis to evaluate perioperative and survival end points.

Results

The study identified 3715 patients, among whom 64.1% (n = 2381) underwent open resection and 35.9% (n

SUBMITTER: Rodriguez-Quintero JH 

PROVIDER: S-EPMC11007735 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature