The structure-function relationship between multifocal pupil perimetry and retinal nerve fibre layer in glaucoma.

ABSTRACT:

Background

Multifocal pupillographic objective perimetry (mfPOP) is a novel method for assessing functional change in diseases like glaucoma. Previous research has suggested that, in contrast to the pretectally-mediated melanopsin response of intrinsically photosensitive retinal ganglion cells, mfPOP responses to transient onset stimuli involve the extrastriate cortex, and thus the main visual pathway. We therefore investigate the correlation between peripapillary retinal nerve fibre layer (pRNFL) thickness and glaucomatous visual field changes detected using mfPOP. Parallel analyses are undertaken using white on white standard automated perimetry (SAP) for comparison.

Methods

Twenty-five glaucoma patients and 24 normal subjects were tested using SAP, 3 mfPOP variants, and o

SUBMITTER: Carle CF 

PROVIDER: S-EPMC11008001 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature