Longitudinal associations between ambient PM_2.5 exposure and lipid levels in two Indian cities.

ABSTRACT:

Background

Exposure to ambient PM_2.5 is known to affect lipid metabolism through systemic inflammation and oxidative stress. Evidence from developing countries, such as India with high levels of ambient PM_2.5 and distinct lipid profiles, is sparse.

Methods

Longitudinal nonlinear mixed-effects analysis was conducted on >10,000 participants of Centre for cArdiometabolic Risk Reduction in South Asia (CARRS) cohort in Chennai and Delhi, India. We examined associations between 1-month and 1-year average ambient PM_2.5 exposure derived from the spatiotemporal model and lipid levels (total cholesterol [TC], triglycerides [TRIG], high-density lipoprotein cholesterol [HDL-C], and low-density lipoprotein cholesterol [LDL-C]) measured longitudinally, adj

SUBMITTER: Anand K 

PROVIDER: S-EPMC11008625 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature