The Trajectory of Successful Aging: Insights from Metagenome and Cytokine Profiling.

ABSTRACT:

Introduction

The longevity is influenced by genetic, environmental, and lifestyle factors. The specific changes that occur in the gut microbiome during the aging process, and their relationship to longevity and immune function, have not yet been fully understood. The ongoing research of other microbiome based on longevity cohort in Kazakhstan provides preliminary information on longevity-related aging, where cytokine expression is associated with specific microbial communities and microbial functions.

Methods

Metagenomic shotgun sequencing study of 40 long-lived individuals aged 90 years and over was carried out, who were conditionally healthy and active, able to serve themselves, without a history of serious infection and cancer, who had not taken any antimicrobials, includ

SUBMITTER: Chulenbayeva L 

PROVIDER: S-EPMC11008724 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature