Serum Nostrin-A risk factor of death, kidney replacement therapy and acute kidney disease in acute kidney injury.

ABSTRACT:

Background

The prediction of Acute Kidney Injury (AKI)-related outcomes remains challenging. Persistent kidney excretory dysfunction for longer than 7 days has been defined as Acute Kidney Disease (AKD). In this study, we prospectively quantified serum Nostrin, an essential regulator of endothelial NO metabolism, in hospitalized patients with AKI.

Design, setting, participants, & measurements

In-hospital subjects with AKI of various etiology were identified through the in-hospital AKI alert system of the Brandenburg University Hospital. Serum Nostrin, and serum NGAL and KIM-1 were measured within a maximum of 48 hours from the timepoint of initial diagnosis of AKI. The following endpoints were defined: in-hospital death, need of kidney replacement therapy (KRT), recovery of

SUBMITTER: Erfurt S 

PROVIDER: S-EPMC11008819 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature