Volume-rendering three-dimensional image analysis of macular neovascularization in age-related macular degeneration.

ABSTRACT:

Background

To visualize and investigate the three-dimensional (3D) images of macular neovascularization (MNV) in eyes with neovascular age-related macular degeneration using optical coherence tomography angiography (OCTA) according to the treatment response to intravitreal aflibercept injection (IVI).

Methods

OCTA images at baseline and 12 weeks (after three loading IVIs) were retrospectively reconstructed as 3D images for patients with type 1 and 2 MNV treated with the "pro-re-nata" regimen. The fluid-free and persistent fluid groups were divided according to the presence of subretinal and intraretinal fluid at 12 weeks after treatment. Using reconstructed 3D images of MNV, the volume, average volume per slice, and z-axis of the volumetric structure were evaluated.

Resul

SUBMITTER: Choi M 

PROVIDER: S-EPMC11009274 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature