Rising Cardiac Troponin: A Prognostic Biomarker for Mortality After Acute Ischemic Stroke.

ABSTRACT:

Background

Elevated cardiac troponin (cTn) is detected in 10% to 30% of patients with acute ischemic stroke (AIS) and correlates with poor functional outcomes. Serial cTn measurements differentiate a dynamic cTn pattern (rise/fall >20%), specific for acute myocardial injury, from elevated but stable cTn levels (nondynamic), typically attributed to chronic cardiac/noncardiac conditions. We investigated if the direction of the cTn change (rising versus falling) affects mortality and outcome.

Methods and results

We retrospectively screened consecutive patients with AIS admitted to 5 stroke centers for elevated cTn at admission and at least 1 additional cTn measurement within 48 hours. The pattern of cTn was defined as rising if >20% increase from baseline, falling if >20% decre

SUBMITTER: Rosso M 

PROVIDER: S-EPMC11010097 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature