Immune cell arrival kinetics to peritoneum and role during murine-experimental trichomoniasis.

ABSTRACT: Trichomonas vaginalis causes trichomoniasis, an inflammatory process related to an increased rate of HIV transmission. In order to study T. vaginalis infection response in a microorganism-free environment, an infection model was established providing a host–parasite interaction system useful to study the interplay between immune cells and the parasite. Infected mice peritoneal cells were immunophenotyped at different times after infection using flow cytometry. Neutrophils and macrophages showed the most relevant increase from third to 12th day post-infection. A high number of B lymphocytes were present on 15th day post-infection, and an increase in memory T cells was observed on sixth day post-infection. The levels of NO increased at day 10 post-infection; no significant influence was obse

SUBMITTER: Rangel-Mata FJ 

PROVIDER: S-EPMC11010205 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature