Outcome measures for Alzheimer's disease: A global inter-societal Delphi consensus.

ABSTRACT:

Introduction

We aim to provide guidance on outcomes and measures for use in patients with Alzheimer's clinical syndrome.

Methods

A consensus group of 20 voting members nominated by 10 professional societies, and a non-voting chair, used a Delphi approach and modified GRADE criteria.

Results

Consensus was reached on priority outcomes (n = 66), measures (n = 49) and statements (n = 37) across nine domains. A number of outcomes and measurement instruments were ranked for: Cognitive abilities; Functional abilities/dependency; Behavioural and neuropsychiatric symptoms; Patient quality of life (QoL); Caregiver QoL; Healthcare and treatment-related outcomes; Medical investigations; Disease-related life events; and Global outcomes.

Discussion

This work provides indicat

SUBMITTER: Ellison TS 

PROVIDER: S-EPMC11010236 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature