Association of acetaminophen use with perinatal outcomes among pregnant women: a retrospective cohort study with propensity score matching.

ABSTRACT:

Background

Although acetaminophen is widely used in women during pregnancy, its safety has not been clearly stated. The study aimed to investigate the association between acetaminophen use and adverse pregnancy outcomes in pregnant women in China.

Methods

We conducted a retrospective cohort study by collecting data on pregnant women who delivered in the Beijing Obstetrics and Gynecology Hospital from January 2018 to September 2023. An acetaminophen use group and a control group were formed based on prenatal exposure to acetaminophen. The pregnancy outcomes that we focused on were stillbirth, miscarriage, preterm birth, APGAR score, birth weight, and congenital disabilities. Pregnant women exposed to acetaminophen were matched to unexposed in a 1:1 ratio with propensity score

SUBMITTER: Xu M 

PROVIDER: S-EPMC11010302 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature