Delineating morbidity patterns in preterm infants at near-term age using a data-driven approach.

ABSTRACT:

Background

Long-term survival after premature birth is significantly determined by development of morbidities, primarily affecting the cardio-respiratory or central nervous system. Existing studies are limited to pairwise morbidity associations, thereby lacking a holistic understanding of morbidity co-occurrence and respective risk profiles.

Methods

Our study, for the first time, aimed at delineating and characterizing morbidity profiles at near-term age and investigated the most prevalent morbidities in preterm infants: bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), mild cardiac defects, perinatal brain pathology and retinopathy of prematurity (ROP). For analysis, we employed two independent, prospective cohorts, comprising a total of 530 very preterm infant

SUBMITTER: Ciora OA 

PROVIDER: S-EPMC11010410 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature