Comparative proteomic analysis of Leishmania parasites isolated from visceral and cutaneous leishmaniasis patients.

ABSTRACT: Leishmaniasis is an infectious disease in which different clinical manifestations are classified into three primary forms: visceral, cutaneous and mucocutaneous. These disease forms are associated with parasite species of the protozoan genus Leishmania. For instance, Leishmania infantum and Leishmania tropica are typically linked with visceral (VL) and cutaneous (CL) leishmaniasis, respectively; however, these two species can also cause other form to a lesser extent. What is more alarming is this characteristic, which threatens current medical diagnosis and treatment, is started to be acquired by other species. Our purpose was to address this issue; therefore, gel-based and gel-free proteomic analyses were carried out on the species L. infantum to determine the proteins differentiating bet

SUBMITTER: Dinc M 

PROVIDER: S-EPMC11010476 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature