Cell repertoire and proliferation of germinative cells of the model cestode Mesocestoides corti.

ABSTRACT: The phylum Platyhelminthes shares a unique population of undifferentiated cells responsible for the proliferation capacity needed for cell renewal, growth, tissue repair and regeneration. These cells have been extensively studied in free-living flatworms, whereas in cestodes the presence of a set of undifferentiated cells, known as germinative cells, has been demonstrated in classical morphology studies, but poorly characterized with molecular biology approaches. Furthermore, several genes have been identified as neoblast markers in free-living flatworms that deserve study in cestode models. Here, different cell types of the model cestode Mesocestoides corti were characterized, identifying differentiated and germinative cells. Muscle cells, tegumental cells, calcareous corpuscle pre

SUBMITTER: Dominguez MF 

PROVIDER: S-EPMC11010542 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature