SSTR2 Mediates the Inhibitory Effect of SST/CST on Lipolysis in Chicken Adipose Tissue.
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SUBMITTER: Zhang X
PROVIDER: S-EPMC11010918 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
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SSTR2 Mediates the Inhibitory Effect of SST/CST on Lipolysis in Chicken Adipose Tissue.
Zhang Xiao X Zhang Jiannan J Huang Tianjiao T Wang Xinglong X Su Jiancheng J He Jiliang J Shi Ningkun N Wang Yajun Y Li Juan J
Animals : an open access journal from MDPI 20240328 7
Somatostatin shows an anti-lipolytic effect in both chickens and ducks. However, its molecular mediator remains to be identified. Here, we report that somatostatin type 2 receptor (SSTR2) is expressed at a high level in chicken adipose tissue. In cultured chicken adipose tissue, the inhibition of glucagon-stimulated lipolysis by somatostatin was blocked by an SSTR2 antagonist (CYN-154086), supporting an SSTR2-mediated anti-lipolytic effect. Furthermore, a significant pro-proliferative effect was ...[more]
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