Association between Multiple Trace Elements, Executive Function, and Cognitive Impairment with No Dementia in Older Adults.

ABSTRACT: Many studies suggest a significant association between individual essential trace elements (ETEs) and cognitive impairment in older adults, but evidence of the synchronized effect of multiple ETEs on cognitive function is lacking. We investigated the association between multiple ETEs, cognitive impairment with no dementia (CIND), and executive function in older Korean adults, using the Bayesian kernel machine regression (BKMR) model. Three hundred and thirty-six older adults were included as the study population and classified as the CIND and control groups. Blood manganese (Mn), copper (Cu), zinc (Zn), selenium (Se), and molybdenum (Mo) were measured as relevant ETEs. The frontal/executive tests included digit symbol coding (DSC), the Korean color word Stroop test (K-CWST), a controlled o

SUBMITTER: Ryoo SW 

PROVIDER: S-EPMC11013674 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature