An Unprecedented Metal Distribution in Silica Nanoparticles Determined by Single-Particle Inductively Coupled Plasma Mass Spectrometry.

ABSTRACT: Metal-containing nanoparticles are now common in applications ranging from catalysts to biomarkers. However, little research has focused on per-particle metal content in multicomponent nanoparticles. In this work, we used single-particle inductively coupled plasma mass spectrometry (ICP-MS) to determine the per-particle metal content of silica nanoparticles doped with tris(2,2'-bipyridyl)ruthenium(II). Monodispersed silica nanoparticles with varied Ru doping levels were prepared using a water-in-oil microemulsion method. These nanoparticles were characterized using common bulk-sample methods such as absorbance spectroscopy and conventional ICP-MS, and also with single-particle ICP-MS. The results showed that averaged concentrations of metal dopant measured per-particle by single-particle I

SUBMITTER: Han J 

PROVIDER: S-EPMC11013762 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature