First-in-human left atrial appendage closure using the WATCHMAN FLX Pro device: a case report.

ABSTRACT:

Background

Device-related thrombosis (DRT) is a known complication to left atrial appendage closure (LAAC). The surface of a LAAC device should ideally have antithrombotic properties. The novel WATCHMAN FLX Pro (WFP) incorporates a fluoropolymer-coated fabric membrane designed to increase thromboresistance and facilitate endothelialization. Such features could potentially allow for a minimal post-procedural antithrombotic regimen. Radiopaque platinum markers at the device shoulders and a large 40 mm device are other novel features of the WFP.

Case summary

A 75-year-old man with atrial fibrillation was referred for LAAC due to prior subdural haemorrhage during direct-acting anticoagulation treatment. He underwent the first-in-human WFP implantation as part of the WATCHMAN FLX

SUBMITTER: Nielsen-Kudsk JE 

PROVIDER: S-EPMC11014679 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature