Dataset Information

Epidemiology, aetiology and diagnosis of congenital hearing loss via hearing screening of 153 913 newborns.

ABSTRACT:

Background

Congenital hearing loss (HL), one of the most common paediatric chronic conditions, significantly affects speech and language development. Its early diagnosis and medical intervention can be achieved via newborn hearing screening. However, data on the prevalence and aetiology of congenital HL in infants who fail newborn hearing screening are limited.

Methods

The sample population included 153 913 infants who underwent newborn hearing screening, and the prevalence of congenital HL, defined as moderate to profound bilateral HL (BHL) or unilateral HL (UHL) (≥40 dB HL), in one prefecture of Japan was measured to minimize the loss-to-follow-up rate, a common factor affecting the screening procedure. Comprehensive aetiological investigation, including physiology, imaging, genetic tests, and congenital cytomegalovirus screening, was performed on children diagnosed with congenital HL.

Results

The calculated prevalence of congenital HL was 1.62 per 1000 newborns (bilateral, 0.84; unilateral, 0.77). More than half of the cases with congenital bilateral or severe to profound UHL showed genetic aetiology or cochlear nerve deficiency (CND), respectively. Approximately 4% and 6% of the cases of congenital BHL and UHL were associated with congenital cytomegalovirus infection and auditory neuropathy spectrum disorder, respectively.

Conclusions

This is an epidemiological and comprehensive aetiological study of congenital HL, as determined via newborn hearing screening according to its severity and laterality, in a large-scale general population of a developed country. Our findings can serve as a reference for optimizing care and intervention options for children with HL and their families.

SUBMITTER: Yoshimura H

PROVIDER: S-EPMC11014784 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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Publications

Epidemiology, aetiology and diagnosis of congenital hearing loss via hearing screening of 153 913 newborns.

Yoshimura Hidekane H Okubo Takuya T Shinagawa Jun J Nishio Shin-Ya SY Takumi Yutaka Y Usami Shin-Ichi SI

International journal of epidemiology 20240401 3

<h4>Background</h4>Congenital hearing loss (HL), one of the most common paediatric chronic conditions, significantly affects speech and language development. Its early diagnosis and medical intervention can be achieved via newborn hearing screening. However, data on the prevalence and aetiology of congenital HL in infants who fail newborn hearing screening are limited.<h4>Methods</h4>The sample population included 153 913 infants who underwent newborn hearing screening, and the prevalence of con ...[more]

PMID: 38609324

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Dataset Information

Epidemiology, aetiology and diagnosis of congenital hearing loss via hearing screening of 153 913 newborns.

Background

Methods

Results

Conclusions

Publications

Epidemiology, aetiology and diagnosis of congenital hearing loss via hearing screening of 153 913 newborns.

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