Replication study identified EFEMP1 association with varicose vein predisposition among Indians.

ABSTRACT:

Background

Varicose vein is a chronic condition that affects the lower extremities of the human body. Several factors have been implicated in the development of this disease, viz age, gender, weight, height and prolonged standing. Recently, genome-wide studies have identified genetic biomarkers that are associated with varicose veins in different ethnic groups. Such genetic studies are lacking in South Asians specifically in Indians where the prevalence of varicose veins is high, and it is important to replicate these variants in the stated population. The study aimed to replicate the association of genetic variants associated with varicose veins in this target population, which were found to be associated with the other ethnic groups.

Methodology

The studied cohort is of th

SUBMITTER: Mehra R 

PROVIDER: S-EPMC11015598 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature