Visual Recovery Time in Patients with Ethambutol-induced Toxic Optic Neuropathy.

ABSTRACT:

Purpose

We aimed to investigate the visual recovery time in patients with ethambutol-induced toxic optic neuropathy (EON) and identify the factors associated with the visual recovery time.

Methods

In this retrospective cohort study, we reviewed the medical records of 35 eyes from 35 patients with EON. Visual recovery was defined as a gain of three or more lines from the nadir.

Results

Patients were observed following discontinuation of ethambutol (EMB), with the mean follow-up period of 21.0 ± 16.0 months. The visual acuity at nadir was logarithm of the minimum angle of resolution 1.4 ± 0.4, and the final visual acuity was logarithm of the minimum angle of resolution 0.6 ± 0.5. Twenty-seven eyes (77.1%) showed significant visual recovery. In Kaplan-Meier survival, the

SUBMITTER: An HR 

PROVIDER: S-EPMC11016690 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature