Impact of early immunosuppression on pediatric liver transplant outcomes within 1 year.

ABSTRACT:

Objectives

The Starzl Network for Excellence in Pediatric Transplantation identified optimizing immunosuppression (IS) as a priority practice improvement area for patients, families, and providers. We aimed to evaluate associations between clinical characteristics, early IS, and outcomes.

Methods

We analyzed pediatric liver transplant (LT) data from 2013 to 2018 in the United Network for Organ Sharing (UNOS) and the Society of Pediatric Liver Transplantation (SPLIT) registries.

Results

We included 2542 LT recipients in UNOS and 1590 in SPLIT. IS choice varied between centers with steroid induction and mycophenolate mofetil (MMF) use each ranging from 0% to 100% across centers. Clinical characteristics associated with early IS choice were inconsistent between the two d

SUBMITTER: Raghu VK 

PROVIDER: S-EPMC11017216 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature