Utilizing systems genetics to enhance understanding into molecular targets of skin cancer.

ABSTRACT: Despite progress made with immune checkpoint inhibitors and targeted therapies, skin cancer remains a significant public health concern in the United States. The intricacies of the disease, encompassing genetics, immune responses, and external factors, call for a comprehensive approach. Techniques in systems genetics, including transcriptional correlation analysis, functional pathway enrichment analysis, and protein-protein interaction network analysis, prove valuable in deciphering intricate molecular mechanisms and identifying potential diagnostic and therapeutic targets for skin cancer. Recent studies demonstrate the efficacy of these techniques in uncovering molecular processes and pinpointing diagnostic markers for various skin cancer types, highlighting the potential of systems genet

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC11018140 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature